Mobile phone records can be used to predict the geographical spread and timing of dengue epidemics, according to a recent study.

More people around the world are becoming vulnerable to this deadly virus as climate change expands the range of the mosquito that transmits dengue and infected travelers spread the disease across borders. Dengue is the most rapidly spreading mosquito-borne disease worldwide. Infection can lead to sudden high fever, bleeding, and shock, and causes significant mortality.

Utilizing the largest data set of mobile phone records ever analyzed to estimate human mobility, researchers at Harvard University developed an innovative model that can predict epidemics and provide critical early warning to policy makers.

"Accurate predictive models identifying changing vulnerability to dengue outbreaks are necessary for epidemic preparedness and containment of the virus," Caroline Buckee, senior author of the study and assistant professor of epidemiology, said in a statement. "Because mobile phone data are continuously being collected, they could be used to help national control programs plan in near real time."

For the study, researchers analyzed data from a large dengue outbreak in Pakistan in 2013 and compared it to a transmission model they developed based on climate information and mobility data gleaned from call records. Data from nearly 40 million mobile phone subscribers was processed in collaboration with Telenor Research and Telenor Pakistan, with the call records being aggregated and anonymized before analysis.

The results showed that the in-country mobility patterns, revealed by the call records, could be used to accurately predict the geographical spread and timing of outbreaks in locations of recent epidemics and emerging trouble spots.

The findings are detailed in PNAS.