The Xavier Musketeers (6) have never made a Final Four in their NCAA Tournament history and will not be given a good chance to do so against the formidable Arizona Wildcats (2).

For the second game in a row, Arizona coach Sean Miller will face off against an old friend, this time with Xavier coach Chris Mack. But despite how well Ohio State coach Thad Matta was supposed to know Miller and his team, Arizona handled the Buckeyes to the tune of 73-58.

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"I don't know if Sean has a funny side," Mack said jokingly in a pregame press conference, according to the Associated Press. "No, he does. I could share a few stories that may either get him embarrassed, maybe even arrested, but I won't do that. I'm kidding about the arrested part. He's got a dry sense of humor. He is a funny guy behind closed doors, but not very often. Not very often. He's ultra-serious. Too serious. He needs to loosen up."

Arizona is widely considered to be a favorite to reach the Final Four and possibly a team that could matchup well with Kentucky, should they meet there. Though Wisconsin won the Western Region's top seed, Arizona may have benefitted, as they were ultimately spared opponents such as Oregon and North Carolina.

While Xavier's offense is not exactly explosive, they are averaging about 73 points per game against Arizona's average of 59 points allowed. The key to beating Arizona is not just scoring on them, as the Wildcats are averaging 76 points per game.