The University of California-San Francisco has received a $100 million gift to support its new Mission Bay hospitals, world-class faculty and students, and research programs focused on the neurosciences and aging, school officials announced.

This donation brings longtime supporter and philanthropist Charles F. "Chuck" Feeney's total UCSF giving to more than $394 million, making Feeney the single largest contributor to the University of California system.

"I get my gratification from knowing that my investments in medical research, education, and the delivery of health care at UCSF will provide lifelong benefits to millions of people not only in the Bay Area but also around the world," Feeney, said in a statement. "I can't imagine a more effective way to distribute my undeserved wealth."

Feeney's gifts to UCSF are most visible at the University's Mission Bay campus, where he has provided indispensable support to create advanced facilities and foster the environment for the biomedical research and patient care that goes on within them.

Before the latest funding, Feeney's most recent gift to the campus was to UCSF Global Health Sciences, enabling the October 2014 opening of Mission Hall, which houses global health researchers, scientists and students under the same roof for the first time. Feeney, who coined the term "giving while living," also generously supported the building of the Smith Cardiovascular Research Building and the Helen Diller Family Cancer Research Building.

Funds will support the $600 million philanthropy goal of the $1.5 billion hospitals project. The latest donation builds upon the transformative $125 million matching gift Feeney made to support the hospitals complex and its programs in 2009, the largest gift received toward the campaign.