Abdominal Fat May Increase Hypertension Risk
ByLocation of body fat may increase hypertension risk, according to a recent study.
Researchers found that people with fat around their abdominal area are more likely to develop hypertension when compared to those with similar body mass index but fat concentrations elsewhere on the body.
Obesity is a known risk factor for hypertension, or high blood pressure, and it is widely reported that the location of fat on a person's body can lead to increased risk of other health issues like heart disease and cancer. However, the relationship between hypertension and overall obesity versus site-specific fat accumulation is unclear, researchers explained in the study.
"Generally speaking, visceral fat stores correlate with the 'apple shape' as opposed to the 'pear shape,' so having centrally located fat when you look in the mirror tends to correlate with higher levels of fat inside the abdomen," Aslan T. Turer, senior author of the study and a cardiologist at the University of Texas Southwestern Medical Center in Dallas, said in a statement.
For the study, researchers collected data from more than 900 patients enrolled in the Dallas Heart Study.
The study participants were followed for an average of seven years to track development of hypertension. Hypertension was classified as a systolic blood pressure of greater or equal to 140, diastolic blood pressure of greater or equal to 90, or initiation of blood pressure medications. Patients also received imaging of visceral fat, or fat located deep in the abdominal cavity between the organs; subcutaneous fat, or visible fat located all over the body; and lower-body fat.
At the end of the study, 25 percent of patients developed hypertension.
While higher body mass index was associated with increased incidence of hypertension, when abdominal fat content, overall fat content and lower-body fat content were factored in, only abdominal fat remained independently associated with hypertension.
The strongest correlation between abdominal fat and hypertension was observed with retroperitoneal fat, which is a type of visceral fat located behind the abdominal cavity and largely around the kidneys.
"The high incidence of hypertension and presence of retroperitoneal fat could suggest that the effects from fat around the kidneys are influencing the development of hypertension," Turer said.
Turer said the finding could open new avenues for the prevention and management of hypertension.
"The finding of the fat around the kidney is a novel one and we do not know specifically what the 'in the mirror' correlates are," Turer explained.
The findings were recently published in the Journal of American College of Cardiology.